Blood transfusions play an important role in patient care. Transfusions of blood and blood products can save the lives of patients who need them because of disease or injury. However, blood transfusions also have risks. For most patients who need blood, the potential benefits far outweigh the risks. This is especially true when healthcare staff are educated and trained to minimize risks. This course is the second in a two-part series on transfusing blood and blood components. This second course in the series focuses on hands-on clinical issues that include how to give blood products safely and how to recognize and respond to transfusion problems.